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ANNOUNCEMENT:  Teleflex has entered into a definitive agreement to divest our Interventional Urology portfolio, including the UroLift System™, Barrigel™ rectal spacer, Deflux™ injectable gel, and Solesta™ bulking agent, to Intersurgical®. This transaction is expected to close in the second half of 2026, subject to customary regulatory approvals and other closing conditions.  We’re excited about this opportunity and remain committed to providing the same high-quality products, reliable service, and on-time delivery our customers expect. We will keep our physicians and patients informed throughout the transition. Please feel free to contact your sales representative with any questions or concerns.

Minimally Invasive Treatment for the Immediate Relief of VUR

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VUR in Children

Symptoms & Causes

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About Deflux

Is it the Right Choice for Your Child?

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My Child Has VUR

Quick Facts & Resources

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Katie’s Story

One Family’s Journey through VUR Treatment

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What is VUR

Urine is made in the kidneys. Normally, urine only flows in one direction – from the kidneys down the ureters and into the bladder. VUR is a condition where urine flows backward from the bladder into the ureters and sometimes back up to the kidneys.

Since urine from the bladder is no longer sterile, VUR can increase the risk of urinary tract infections and may cause long-term kidney damage if left untreated.

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The Deflux Advantage

Deflux is an injectable gel used to treat VUR. It is injected at the spot where the ureter connects to the bladder. This will help keep urine from flowing back into the ureters and kidneys. Eventually, new tissue grows around the gel providing long-term results.

The procedure usually takes about

15 minutes

and allows children to go back to normal activities the next day.

Safe Treatment for VUR

Deflux has been used safely for over two decades to treat children with VUR.2

 

More than

400,000

Procedures performed to date3

Deflux - Effective Treatment for VUR

Deflux works well to treat VUR with the majority of children having success after one injection.4

In long-term studies, after one injection of Deflux:

93%

had no fUTIs within 19 months4

“We choose Deflux because it was simple and it offered very good results.”

– Sam, Mother of a patient with VUR

Watch Katie’s story now

REFERENCES:

1. Cerwinka WH, Scherz HC, Kirsch AJ. Endoscopic treatment of vesicoureteral reflux with dextranomer/hyaluronic acid in children. Advances in Urology. 2008; 1-7.
2. Restylane® celebrates 25 years of natural-looking results with its signature line of hyaluronic acid fillers. 2021. Accessed: June 21, 2023. https://www.prnewswire.com/news-releases/restylane-celebrates-25- years-of-natural-looking-results-with-its-signature-line-of-hyaluronic-acid-fillers-301388779.html.
3. Data on file. Palette Life Sciences.
4. Kalisvaart JF, Scherz HC, Cuda S, Kaye JD, Kirsch AJ. Intermediate to long-term follow-up indicates low risk of recurrence after double hit endoscopic treatment for primary vesicoureteral reflux. J Pediatr Urol. 2012;8(4):359-36.

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